TRANSFORMATIVE CANCER THERAPIES. TARGETED IMPACT.
Immunotherapy represents one of the greatest advances for people living with cancer, but off-target effects remain a challenge in the clinical setting.
Our technology is designed to unleash validated and proven proinflammatory mechanisms on tumors while preventing unwanted side effects on non-target tissue. We create systemically delivered targeted therapies that address the limitations of immuno-oncology.
Werewolf Therapeutics is a highly innovative company striving to redefine the cancer treatment landscape with potential best-in-class therapies.
Our technology is designed to unleash validated and proven proinflammatory mechanisms on tumors while preventing unwanted side effects on non-target tissue. We create systemically delivered targeted therapies that address the limitations of immuno-oncology.
Werewolf Therapeutics is a highly innovative company striving to redefine the cancer treatment landscape with potential best-in-class therapies.
OUR GOAL IS TO TRANSFORM THE LIVES OF CANCER PATIENTS
INNOVATIVE CANCER THERAPIES DIFFERENTIATED BY DESIGN
We are advancing a novel class of cancer biotherapeutics designed to enhance the body’s immune response to cancer.
These conditionally activated proinflammatory immune modulators, called INDUKINE™ molecules, are systemically administered in an inactive form and are selectively activated to deliver full biological potency of cytokines upon entering the tumor microenvironment.
Our team of experienced scientists invented our proprietary PREDATOR™ protein engineering technology to design and engineer the future of immuno-oncology biotherapeutics for patients.
WATCH: How PREDATOR™ maximizes therapeutic potential while minimizing unwanted off-target effects
What’s in a name?
The company name is a powerful analogy to our scientific approach. A werewolf is a creature that goes unnoticed in day-to-day life but transforms into a dangerous predator under specific conditions. That is exactly what the medicines that we are developing do.
Our molecules are delivered systemically and remain inactive in the body as they are drawn to the tumor microenvironment, at which point they stimulate a powerful immune response and unleash an attack on cancer cells.
Our molecules are delivered systemically and remain inactive in the body as they are drawn to the tumor microenvironment, at which point they stimulate a powerful immune response and unleash an attack on cancer cells.
Our proven team
Our team brings together the unmatched determination and dedication of experienced physician-scientists and industry veterans with a proven track record in oncology drug development. Our combined expertise in oncology, immunology, and protein engineering is key for delivering effective cancer immunotherapies to the clinic and market to improve the lives of people who are living with cancer.
Meet our Team
Dan Hicklin, Ph.D.
President, Chief Executive Officer and Board member
Cynthia Seidel-Dugan, Ph.D.
Chief Scientific Officer
Tim Trost
Chief Financial Officer
Reid Leonard, Ph.D.
Chief Operating Officer
Ellen Lubman, M.B.A.
Chief Business Officer
Randi Isaacs, M.D.
Chief Medical Officer
Press Releases
September 1, 2022
Werewolf Therapeutics Announces Initiation of Patient Dosing in Phase 1/1b Clinical Trial of WTX-124 for the Treatment of Patients with Selected Solid Tumors
First clinical candidate of a new class of systemically delivered conditionally activated INDUKINE™ therapeutics developed
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August 11, 2022
Werewolf Therapeutics Reports Second Quarter 2022 Financial Results and Provides Business Highlights
FDA granted IND clearance for lead candidate WTX-124 for evaluation as a treatment for advanced
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August 3, 2022
Werewolf Therapeutics to Participate in the 2022 Wedbush PacGrow Healthcare Virtual Conference
Werewolf Therapeutics, Inc. (Nasdaq: HOWL), an innovative biopharmaceutical company pioneering the development of conditionally activated
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Join Our Team
Are you someone who makes things happen? Do you want to work at a company that embraces the same ideals? We’re looking for vibrant, creative, forward-thinking people to join our team. Click the link below and let us know that you’re interested. We’d love to talk to you.
Scientist, Pharmacology
The successful candidate will be a creative scientist with strong problem-solving skills and demonstrated experience in in vitro and in
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Senior Scientist, Process Development
As a key member of the CMC function this position will primarily be responsible for the development, optimization, and troubleshooting
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Research Scientist III, Protein Biochemistry
The successful candidate will be a creative scientist, with strong problem-solving skills and demonstrated experience in protein biochemistry and antibody/therapeutic
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