Our Science
TRANSFORMING CANCER TREATMENT THROUGH INNOVATION
Our proprietary PREDATOR™ protein engineering technology integrates specialized protein design elements to enhance activity, stability and tumor selectivity within a single molecule. These are called INDUKINE™ molecules.
Systemic Delivery
Tumor Microenvironment
Immune cell receptor
Protease
Half-life extension domain
Cytokine domain
Inactivation domain
Protease-cleavable linkers
INDUKINE™ molecules are systemically administered in an inactive form and, upon entering the tumor microenvironment, are selectively activated to deliver the full biological potency of cytokines and recruit a powerful anti-tumor immune response. Therefore, INDUKINE™ molecules deliver maximum therapeutic potential while minimizing unwanted off-target effects in non-tumor tissues.
How PREDATOR maximizes therapeutic potential while minimizing unwanted off-target effects
Predator™ Protein Engineering
Our proprietary PREDATOR™ protein engineering technology allows us to achieve immune targeting and conditional activation in a new way, enabling the development of novel therapies designed to:
