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Our Science

TRANSFORMING CANCER TREATMENT THROUGH INNOVATION

Our proprietary PREDATOR™ protein engineering technology integrates specialized protein design elements to enhance activity, stability and tumor selectivity within a single molecule. These are called INDUKINE™ molecules.

Systemic Delivery
Tumor Microenvironment
Immune cell receptor
Protease
Half-life extension
domain
Cytokine domain
Inactivation domain
Protease-cleavable linkers

INDUKINE™ molecules are systemically administered in an inactive form and, upon entering the tumor microenvironment, are selectively activated to deliver the full biological potency of cytokines and recruit a powerful anti-tumor immune response. Therefore, INDUKINE™ molecules deliver maximum therapeutic potential while minimizing unwanted off-target effects in non-tumor tissues.

Predator™ Protein Engineering

Our proprietary PREDATOR™ protein engineering technology allows us to achieve immune targeting and conditional activation in a new way, enabling the development of novel therapies designed to:
1
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Exhibit superior tolerability and drug-like properties when administered systemically as inactive pro-drugs
2
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Undergo transformation to the active state only upon reaching the tumor microenvironment
3
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Deliver full biological potency of antitumor immune modulation for maximum therapeutic potential