Our Science
TRANSFORMING CANCER TREATMENT THROUGH INNOVATION
Our proprietary PREDATOR™ protein engineering technology integrates specialized protein design elements to enhance activity, stability and tumor selectivity within a single molecule. These are called INDUKINE™ molecules.
INDUKINE™ molecules are systemically administered in an inactive form and, upon entering the tumor microenvironment, are selectively activated to deliver the full biological potency of cytokines and recruit a powerful anti-tumor immune response. Therefore, INDUKINE™ molecules deliver maximum therapeutic potential while minimizing unwanted off-target effects in non-tumor tissues.
Predator™ Protein Engineering
INNOVATIVE OPPORTUNITIES FOR PREDATOR™ PLATFORM
Our PREDATOR™ protein engineering technology allows us to create INDUKINE™ molecules for tissue-specific inflammatory diseases where modulating the immune system can offer therapeutic benefits while minimizing unwanted off-target effects in healthy tissues.
Non-Oncology INDUKINE™ Therapeutics
- Inflammation
- Other diseases
Expanding Conditional-Activation Technology to New Modalities
- Targeted antibodies, T cell engagers, ADCs
- Cell-based therapies
- Disease-specific linkers